[用于精子DN**段化指数高的不育患者的卵胞浆内单精子注射植入前遗传筛查]

摘要

在里面英语，中国人

目的：探讨植入前遗传筛查（PGS）在卵胞浆内单精子注射（ICSI）和胚胎移植（ET）中对精子DN**段化指数（DFI）高的不孕患者的应用价值。

方法：我们选择了2015年4月至2016年10月在我中心接受ICSI-ET治疗的90例不孕患者，其中60例精子DFI=≥15%，30例精子DFI

结果：高，低DFI-ICSI组胚胎着床率差异有统计学意义（31.25 vs 52.50%，P

0.05），优质胚胎（[62.41±25.97]vs[73.00±22.10]，P>0.05），或囊胚形成（[62.55±25.21]vs[64.30±18.60]，P>0.05）。高DFI-PGS的胚胎着床率显着高于高DFI-ICSI组（60.97%vs 31.25%，P

0.05），优质胚胎（[64.42±30.75]vs[62.41±25婴儿试管是不是都是双胞胎.97]，P>0.05）和胚泡形成（[67.53±19.24]vs[62.55±25.21]，P>0.05）。

结论：对于精子DFI=≥15%的不孕患者，PGS-ICSI而非ICSI可显着提高胚胎着床率。

Objective:To investigate the application value of the inclusion of preoperative studies（PGS）on high-liver DNA indicators（DFI）.Method：In 2015 In In In 2015 In In In In In 2015 In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In In patpatI tretreathetretretretreathepatICSI≥15%In In In In In In In In In In the patpatpatICSI ICSI ICSI ICSI ICSI≥15南方39%In In In In In In In In In The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The patient 30 cases of PGS detection is high DFI-ICSI group;can be DFI<30%patpatien30 patien30%of ICSI coSI treatment were effed of DFI-ICSI group.The DFI-ICSI group与DFI-ICSI group相比，DFI-ICSI group The infacitititimulmulmulmultitificiciThe affi-ICSI group更高，The The The The The The The dididididiICSI group更高，The The The dididicomposis，The The didicomposis，The didicompososis，The didicomposososis，The didididididicompososososis，The dididididididididididididididididididididididididididididididicompososososrat，The didididididididididididididiThe factoresafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafaf较高与较高的DFI-ICSI afafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafafThe The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The The红细胞计数，FSH，LH，T，DFI，**白The compototototcoco**ththmonthmonththmococostststststststststststststststststststststststststststcocoststststststststststststststststststststststststststststcoststststststcostststststststststststststststcoststststststcoststststststststststststststststs:高DFI-ICSI ICSI tistststfistststststststststststststststststststststststststststststststststststststs:高DFI-ICSI ICSI ICSI tiststfiststststststststststDFI-ICSI tissues interrelated，severe receptor rate[（65.38±24.62）%vs（73.00±17.00）%]，excessive rate[（62.41±25.97）%vs（73.00±22.10%）]，severe formation rate[62.55±25.21）%vs（64.30±18.60）%]无统计学差异（Pß>0.05），骨量增加[31.25%vs 52.50%]有统计学差异（P

0.05），（60.97%vs 31.25%）的结果显示_øøøøøøøø期死亡率（60.97%vs 31.25%）与（67.53±19.53±19.24）%vs（62.55±25）%）与（P_.55±25%）与（P_.55 Signification义（P

关键词：胚胎植入;胚胎修复;卵胞浆内单精子注射;精子DN**段化指数;植入前遗传筛选。